Dapagliflozin
Dapagliflozin is a prescription drug that belongs to the class of sodium-glucose co-transporter 2 (SGLT 2) inhibitors. Its function is to control blood sugar levels in people with type 2 diabetes. This drug is only available in tablet form.
For pregnant and breastfeeding mothers, this drug is in category C. This means that the drug may be used with caution if the benefits outweigh the risks to the fetus. Animal studies have shown risks to the fetus. However, there has been no direct research on pregnant women.
Drug trade names : Dapagliflozin, Dapagliflozin+Metformin, Forxiga, and Xigduo XR.
Benefits of Dapagliflozin
This drug is able to control blood sugar levels in the body, especially for people with type 2 diabetes. Dapagliflozin works by increasing the kidney’s ability to reduce reabsorption or reabsorption of glucose. Thus, glucose is excreted through urine, and blood sugar levels are reduced.
Dapagliflozin Side Effects
Various side effects that may arise from this drug, namely:
- Genital mycotic infections (such as vulvovaginitis and balanitis), hypotension, bone fractures, UTI, increased hematocrit levels.
- Dizzy.
- Nausea, constipation, thirst, dry mouth.
- Nasopharyngitis.
- Excessive sweating.
- Dysuria, polyuria, nocturia.
- Back pain.
- Urticaria, angioedema, hyperhidrosis, rash.
- Pain in the extremities.
- Faint.
If after taking this medicine these side effects or other effects persist or worsen, see a doctor immediately or seek medical help.
Dapagliflozin Dosage
The dosage of the drug may vary for each individual. Therefore, discuss with your doctor before using this drug to get the right dosage.
However, the dose to treat type 2 diabetes in adults is 5 milligrams per day or can be increased to 10 milligrams taken once a day.
How to Use Dapagliflozin
Always follow your doctor’s advice and read the instructions on the label. This medicine can be taken with or without meals. The initial dose given by the doctor is usually low, then increased if necessary.
Do not increase or decrease the prescribed dose without your doctor’s instructions. Take this medication regularly at the same time every day for maximum effect.
Cautions for Using Dapagliflozin
There are several things to consider before taking this drug. For example, tell your doctor if you have a history of allergies to any drugs, especially the SGLT 2 class of drugs when prescribed by your doctor. You also need to tell your doctor about the drugs, supplements, and herbal products you are currently taking.
Inform your doctor if you are undergoing regular dialysis or have impaired kidney function. You should also talk to your doctor if you are breastfeeding, planning a pregnancy or planning surgery, including dental surgery.
Dapagliflozin Interactions
Interactions may occur if dapagliflozin is used together with other medicines. That is why it is important to inform your doctor about the medicines you are taking.
The risk of dehydration and hypertension may increase if the drug is used with diuretic drugs. In addition, the risk of hypoglycemia may also increase if this drug is used together with insulin and sulfonylurea drugs.
Dapagliflozin Contraindications
This drug is not recommended for consumption by people with type 1 diabetes or diabetic ketoacidosis and someone who has a history of allergies to dapagliflozin or similar drugs.