Amoxicillin Trihydrate
Amoxicillin trihydrate is an antibiotic to treat bacterial infections, such as sore throat, diarrhea, pneumonia, and ear infections. You can only get this medicine with a doctor’s prescription. Make sure you have consulted a doctor first.
Both adults and children can consume it. In pregnant women, animal studies have shown no risk to the fetus. This antibiotic drug, which is in the penicillin category, can also be absorbed into breast milk.
That is why, both pregnant and breastfeeding mothers need to consult a doctor before consuming it. Amoxicillin trihydrate is available in tablet, capsule, syrup, and injection forms.
Amoxicillin Trihydrate Dosage
The doctor will adjust the dosage based on age, weight, form of the drug, type of disease, and its severity. Amoxicillin trihydrate in injection form can only be given by a doctor.
The injectable form is generally used to treat meningitis or endocarditis. Here are the general doses of amoxicillin in tablet, capsule, and syrup forms:
1. Sinusitis
- Adults and children weighing more than 40 kilograms: 250–500 milligrams every eight hours. The doctor may increase the dose in cases of severe infection to 750–1,000 milligrams, every 8 hours.
- Children over three months: 20–90 milligrams per kilogram of body weight per day.
You can also use the above dosage to treat mouth and throat abscesses, otitis media, severe urinary tract infections, skin infections and kidney infections.
2. Streptococcus infection
Streptococcus bacteria are often the cause of pharyngitis or tonsillitis. The dosage is:
- Adults: 500 milligrams every 8 hours. In cases of severe infection, the dose can be increased to 750–1,000 milligrams every 8 hours, for 10 days.
- Children weighing less than 40 kilograms: the dose is 40–90 milligrams per kilogram of body weight per day.
3. Tooth Abscess
For adults, the dose is 3,000 milligrams every eight hours twice a day.
4. Helicobacter pylori infection
To treat Helicobacter pylori infection in adults, the dose is 750–1,000 milligrams twice daily for 7–14 days. Antibiotics can generally be combined with other antibiotics and proton pump inhibitors (PPIs).
5. Typhoid and paratyphoid fever
- Adults: 500–2,000 milligrams which you can take every eight hours.
- Children weighing under 40 kilograms: 100 milligrams per kilogram of body weight, which you can divide into 3 doses.
6. Urinary tract infection
In adults, the dose is 3,000 milligrams. You can continue the dose after 10–12 hours.
7. Pneumonia
- Adults: 500–1,000 milligrams every 8 hours.
- Children under three months: 20–90 milligrams per kilogram of body weight daily.
8. Gonorrhea
For adults, a single dose of 3,000 milligrams is given. Amoxicillin is then combined with probenecid.
Recommended Drugs Containing Amoxicillin
Medicines containing amoxicillin are available in the form of tablets, capsules, and dry syrup. Here are recommendations for medicines containing amoxicillin and you can buy them through the Halodoc Health Store :
- Amoxsan 500 mg 10 Capsules. Contains Amoxicillin trihydrate 500 mg which works by inhibiting cell wall biosynthesis, thus killing bacteria.
- Lapimox 500 mg 10 Caplets . Antibiotic of choice to kill gram-positive and gram-negative bacteria organisms that are sensitive to Amoxicillin.
- Yusimox Forte Dry Syrup 250 mg/5 ml 60 ml. Dry syrup that can be consumed by children and adults to treat respiratory tract infections, gonorrhea, to skin and soft tissue infections.
- Supramox 500 mg 10 Capsules. A drug containing Amoxicillin 500 mg can be used as a treatment for genitourinary tract infections and respiratory tract infections.
- Amoxsan Forte Dry Syrup 60 ml. Used for infections caused by bacteria such as Streptococcus, E. coli, H. influenzae, P. mirabilis, to N. gonorrhea.
- Yusimox 500 mg 10 Caplets . Antibiotics containing Amoxicillin trihydrate which is effective in killing infections caused by gram-positive and gram-negative bacteria.
Benefits of Amoxicillin Trihydrate
Amoxicillin trihydrate is useful for treating all kinds of bacterial infections. It works by stopping the growth of bacteria.
This drug is often combined with other drugs by doctors to treat stomach ulcers caused by H. pylori bacterial infections. The goal is to kill the bacteria and prevent ulcers from returning.
Penicillin can only treat bacterial infections, so it won’t be effective if you use it to treat a viral infection. Taking it when you don’t need it can reduce its effectiveness in the future when it is needed.
How to Use Amoxicillin Trihydrate
Here’s how to use amoxicillin trihydrate based on the form of the drug:
1. Tablets and capsules
- Take this medication by mouth with or without food as directed by your doctor.
- To make it easier to swallow, you can swallow it with water.
- Take this antibiotic at evenly spaced intervals. To help you remember, take this medication at the same time(s) every day.
- Take the full dose your doctor has prescribed, even if symptoms go away. Stopping the medication too early may allow the bacteria to continue to grow, leading to reinfection.
2. Syrup
- Shake the bottle before consuming it.
- Use a measuring spoon or cup to get the right dose.
- Do not use a household spoon as it cannot measure the correct dose.
- Take the medication at evenly spaced intervals. To make it easier to remember, take this medication at the same time every day.
- Take the full dose your doctor has prescribed, even if your symptoms have gone away. Stopping too soon may allow the bacteria to continue to grow, leading to reinfection.
Caution in Using Amoxicillin Trihydrate
There are several things you need to pay attention to before taking amoxicillin trihydrate, including:
- Tell your doctor if you are allergic to amoxicillin or other penicillin antibiotics.
- Inform your doctor about your medical history. For example, kidney disease, viral infections, and liver disease.
- Tell your doctor if you are planning to or have received any live bacterial vaccinations, such as typhoid vaccine. Amoxicillin may make the vaccine not work as well.
- You also need to tell your doctor if you have any scheduled surgery, including dental surgery.
- Tell your doctor about other medicines you are taking, including supplements and herbal products.
- Finish the antibiotics prescribed by the doctor even if the condition has improved.
Amoxicillin Trihydrate Side Effects
Amoxicillin trihydrate rarely causes side effects if you take it correctly. Mild side effects that can occur are nausea, vomiting, and diarrhea.
Long-term or repeated use can potentially cause candidiasis or fungal infections in the mouth or vagina. Signs include the appearance of white patches in the mouth or vaginal discharge.
There are signs of serious side effects that you need to be aware of, namely:
- Nausea and vomiting that doesn’t stop.
- Loss of appetite.
- Stomach ache.
- Yellowing of the eyes and skin.
- Dark-colored urine.
- Easy bruising or bleeding.
- Diarrhea that doesn’t stop.
- Slimy stools.
You also need to be aware of drug allergy symptoms, such as:
- Fever that doesn’t go away.
- Swollen lymph nodes that get worse.
- Rash.
- Itchy.
- Swelling of the face, tongue, and throat.
- Severe headache.
- Difficulty breathing.
Amoxicillin Trihydrate Interactions
Drug interactions can decrease effectiveness and increase the risk of serious side effects. Products that can interact with trihydrate are methotrexate. The drug functions as a drug to treat cancer.
Amoxicillin can also affect the results of laboratory tests. It can cause false positive results on certain urine tests for diabetes. Talk to your doctor or laboratory personnel if you are taking amoxicillin trihydrate.
Contraindications of Amoxicillin Trihydrate
Contraindications are conditions that make someone not advised or not allowed to undergo certain treatments. Amoxicillin trihydrate is not recommended for someone who is allergic to this drug or other types of antibiotics.