Allylestrenol: Benefits, Side Effects and Dosage

What are the drugs to strengthen the womb of young pregnant women? One of them is Allylestrenol. Allylestrenol is a drug containing synthetic progesterone which is often used in progesterone hormone replacement therapy. This hormone drug is generally given to women who are at risk of miscarriage due to progesterone hormone deficiency.

The way this drug works is similar to natural progesterone, namely forming a strong placenta so that it can maintain the fetus in the womb. Allylestrenol can also reduce the sensitivity of the uterus to the hormone oxytocin which can trigger contractions.

With the right dosage, this drug can prevent potential miscarriage and premature birth. Allystrenol is also safe for the development of the baby in the womb, especially in cases of intrauterine growth retardation.

Class: Prescription drugs.

Category: Progesterone hormone replacement therapy.

Benefits: Prevents miscarriage in women who have progesterone hormone deficiency. Allylestrenol also functions to prevent premature birth.

Allylestrenol for pregnant and lactating mothers: For pregnant women, this drug is safe to consume. However, the amount and dosage of its use must be in accordance with the doctor’s prescription. This drug should not be consumed carelessly.

Meanwhile, for breastfeeding mothers, it is best not to take this drug without a doctor’s recommendation.

Drug form: Tablets Trademarks: Nobor, Preabor, Pregtenol, Pregnabion, Pregnolin.

Benefits of Allylestrenol

What is the use of Allylestrenol? Here are the various benefits of allylestrenol:

  • Strengthens the attachment of the embryo to the uterus and increases blood flow to the placenta.
  • Prevent recurrent miscarriage.
  • Prevent premature birth.
  • Relaxes the uterine muscles to prevent contractions.
  • Treating intrauterine growth retardation or stunted fetal growth.
  • Treating amenorrhea, which is not experiencing menstruation due to a lack of progesterone.
  • Relieves symptoms of premenstrual syndrome, such as mood swings, tender breasts, food cravings, fatigue, irritability, and stress.
  • Treating hot flashes or heat strokes in postmenopausal women
  • Treats benign prostatic hyperplasia, a noncancerous increase in the size of the prostate gland in men.

Warnings Before Taking Allylestrenol

Allylestrenol is not sold freely and should not be consumed carelessly. This drug can only be obtained through a doctor’s prescription and its use must be under the supervision of a doctor.

Here are some things you need to pay attention to when taking this medicine: 

  • Make sure you are not allergic to the ingredients contained in this medicine. Therefore, tell your doctor if you have a history of allergies to allylestrenol or other types of allergies.
  • Inform your doctor if you have liver disease or have a history of it. Because someone who has impaired liver function is not recommended to take this drug.
  • Tell your doctor if you have or have a history of diabetes, either before or during pregnancy (gestational diabetes).
  • Inform your doctor if you have a history of hypertension, vaginal cancer, and breast cancer before taking this medication.
  • People with asthma and respiratory disorders should also check with their doctor before using this medication.
  • Allylestrenol can decrease concentration and cause visual disturbances. Therefore, avoid driving or operating heavy machinery after taking this medication.
  • Be careful if you have ever received medical treatment related to depression before using this medicine.
  • This medication may also pass into breast milk. Therefore, tell your doctor if you are breast-feeding.
  • Inform your doctor about other medicines you are taking, including supplements, or herbal products. This is important to prevent allergic reactions to the drug.

Allylestrenol Dosage

The dosage for each person can vary, depending on the condition. Here are the general dosages for allylestrenol:

  • Miscarriage: the dose is 5 milligrams which you can take three times a day for 5-7 days. The duration of use can be extended according to the doctor’s advice. Then you can reduce the dose gradually if the symptoms have disappeared.
  • Recurrent miscarriage: the dose ranges from 5-10 milligrams per day and you need to take it after confirming pregnancy. The duration of use depends on the doctor’s assessment. Generally, doctors stop it gradually if the pregnant woman has passed the critical period.
  • Preventing premature birth: the dosage varies, depending on the results of the doctor’s examination and the patient’s needs. However, the dosage should not exceed 40 milligrams per day.

How to Use Allylestrenol

When are pregnancy-enhancing drugs given? Use this drug according to the doctor’s instructions. Make sure you read the information on the drug packaging label before consuming it. This drug can generally be consumed before or after meals.

Some people may need to take allylestrenol with or after food to prevent indigestion. You can drink water or eat food, such as a banana, to swallow allylestrenol tablets. Follow the storage instructions on the packaging.

How to Store Allylestrenol

Here’s how to properly store allylestrenol:

  • Keep out of reach of children.
  • Store at room temperature, around 15-25 degrees Celsius.
  • Avoid direct exposure to sunlight.
  • Do not store in damp places.
  • Place in a cool location. Avoid storing it in the freezer.